Endocrine Abstracts

Background: Since it has been shown that markers of oxidative stress persist in endothelial cells that have been exposed for a prolonged time to chronic constant high glucose levels, long after glucose normalization, a phenomenon defined as ‘metabolic memory’, evaluation of chronic exposure to oscillating high glucose, its impact on the induction of cellular stress markers and the onset of a ‘metabolic memory’ might be of pivotal interest. In doing so we al...